As researchers increasingly combine native mass spectrometry with top-down fragmentation, they are facing many challenges in their quests to learn about the protein sequence as well as the higher-order structure. It is often challenging and time-consuming to develop protocols as well as to interpret the results of these studies. The Consortium has started this Sub-Committee to dive into these challenges and improve researchers’ abilities to probe the detailed structure of proteins. The study is being coordinated by Frederik Lermyte of the University of Warwick.
